The mod I used is also for the same patch and build.

There will come certain minutes where certain choices will slice off access to different missions (say, speculatively, picking some side in a warmed verbal confrontation), yet generally, you can get far into the fundamental journey before expecting. I'm using the latest F4SE for that patch (build 0.6.21). Fallout 4's fundamental journey is far more convincing than past recreations in the arrangement. I have the latest Fallout 4 patch (1.10.163). I launch the launcher and my settings there have changed. It still keeps opening in windowed mode, at some tiny 16:9 resolution. I run F4SE as an administrator, I run Mod Organizer as an admin, I tried the High DPI resolution fix, I tried the 'managed controlled folder access' trick (all that did was make it so I couldn't save files to other folders, so I had to turn it off), I uninstalled and reinstalled the game (deleted everything related to fallout 4 on my computer), even installed in a place other than program files. ExpandedLauncher is launcher replacement for Fallout 4 which aims to bring controller support and script extender compatibilty. I did everything older posts with the same problem had and it still doesn't work. But I can't find the equivalent for Fallout 4, probably simply because I don't know the name of it. Tried this several times and every single time it did the same thing. When I played Fallout New Vegas, I remember using something called Sexout, which seemed from a user standpoint to be pretty much a clone of SexLab. Fallout 4 Script Extender (F4SE) by Ian Patterson, Stephen Abel, and Brendan Borthwick (ianpatt, behippo, and purplelunchbox) Fallout 4 runtime 1.10.130 - build: 0.6. All of my settings are reverted to default (pipboy color, hud color, audio and gamplay settings). honestly, I don't even know what resolution it is. Launched the game with just the script extender installed and one mod that needed it from Mod Organizer with the F4SE. The game launched properly without downsizing the resolution or resetting my game settings.

Launched the game a second time without the script extender just to see if it was Fallout 4's issue. Launched the launcher first, chose my settings, even made sure they were the same across all. It keeps launching in windowed small mode, as I'm now calling it.

Fallout 4 skript extender